Medicating Your Fish - Tips and Dosages

 

by Doug Sweet, Curator of Fishes, Belle Isle Aquarium

  

This information was requested by after Doug spoke at a Michigan Cichlid Association meeting. Thanks, Doug for passing it on.  This was printed in the May-June 2001 issue of Fincinnati.

 

Oral Medications for Fish (Taken from Stoskopf’s Fish Medicine)

Metronidazole   - 50 mg/kg OID for 5 days

                         - 1 gram/100 grams food OID for 5 days

Thiabendazole - 66 mg/kg OID, twice 10 days apart

 

Mebendazole   - 20 mg/kg weekly for three treatments (for Nematodes)

 

Fenbendazole - 11mg/kg OID twice

 

Praziquantel    - 400 mg/100 grams OID for 7 days (trematodes)

                        - 500 mg/kg once (cestodes)

 

Nitrofurazone  - 50 mg/kg OID for bacterial enteritis

                        - 75 - 100 mg/kg OID 5 - 15 days for microsporidial infections

 

Potassium permanganate Stock Solution:

- 1.52 grams KMnO4 in 100 ml water

- Use 10 ml of the above solution per 20 gallons of water to achieve 2 ppm.

 

Malachite Green Stock Solution

- 3.7 grams of zinc-free malachite green added to 1 liter of water or formalin

            (use .6 to 1.0 ml of this stock per 10 gallons of water)

 

Citric Copper Sulfate Stock Solution

- 21 grams crystal Copper sulfate pentahydrate (CuSO4-5 H2O)

- 21 grams citric acid crystals

- 473 ml water

- one drop of this solution per gallon gives .15 ppm

- 1ml per 20 to 25 gallons should give .15 ppm

 

 

Drug Dosages for Fish Disease Treatments at Belle Isle Aquarium

Formalin and Formalin/Malachite Stock  -  15 - 25 ppm (.6 - 1.0 ml per 10 gallons) Solutions

 

Copper sulfate - freshwater - .5 - 1.0 ppm

                        saltwater - .15 - .20 ppm maintained at constant level by daily test and re-dosing

Potassium permanganate - 1.0 - 2.0 ppm  (which can be reversed by .38 ml per gallon Hydrogen                                                               peroxide)

 

Dylox (Masoten, Trichlorfon) - .25 ppm

 

Malachite Green - .1 ppm

 

Metronidazole - 6 ppm

 

Praziquantel (Droncit) - .25 - 3.5 ppm (3 X 34 mg tablets per 10 gallons)

 

Levamisole (13.65% injectable) - 2 ppm (1.1 ml per 20 gallons)

                                                             1 Discomed capsule per 8 gallons

 

Nitrofurazone - 10 ppm

 

 

Precalculated Treatments

Size of Tank            Formalin/Malachite    CuSO4          KMnO4        Nitro.     Praziquantel

(Gallons)            Green/ Stock Soln.      Stock               Stock

20                     1.2 - 2.0 ml                  1 ml                  10 ml        .8 grams   .2 grams

35                     2.1 - 3.5 ml                  1.75 ml             18 ml        1.3 g         .4 g

45                     2.7 - 4.5 ml                  2.25 ml             23 ml        1.7 g         .5 g

100                    6 - 10 ml                     5 ml                  50 ml        3.8 g        1.3 g

165                   10 - 16 ml                    8 ml                  83 ml         6.2 g       2.2 g

325                   20 - 32 ml                    16 ml                162 ml        12 g        4.3 g

650                   39 - 65 ml                    32 ml                325 ml        24 g        8.6 g

1400 (#41)         84 - 140 ml                  70 ml                700 ml        53 g       15 g

1600 (cold water) 96 - 160 ml                 80 ml                800 ml        61 g       18 g

 

2800                 168 - 280 ml               140 ml              1400 ml      106 g        32 g

(cool water & #11)

4000 (GLT, B-3) 240 - 400 ml               200 ml              2000 ml      151 g        45 g

 

 

Salt Quantities (Volume & Weight) used at Belle Isle Aquarium for Treating Fish Diseases

 

Size of Tank (gallons)                 1/4 Isotonic                         1/2 Isotonic            

20                                             .63 cups (170 grams)           1.25 cups (340g)  

35                                             1.1 cups (297.5 g)                2.2 cups (595 g)

45                                             1.4 cups (383 g)                   2.8 cups (765 g)

100                                           3 cups (850 g)                      6 cups (1.7 kg)

165                                           5 cups (1.4 kg)                    10 cups (2.8 kg)

325                                           10 cups (2.8 kg)                  20 cups (5.6 kg)

650                                           20 cups (5.6 kg)                  11.2 kg

1400                                         12 kg                                  24 kg

1600                                         14 kg                                  27 kg

2800                                         24 kg                                  48 kg

4000                                         34 kg                                  68 kg

 

Protozoan parasites like ich, trichodina, costia, chilodonella, epistylus, scyphidia, trichophrya, etc. can all be treated with formalin.  Formalin malachite green stock mixture can also be used, especially for ich. I like to use formalin/malachite green mixture plus 1/4 to 1/2 isotonic salt solution for persistent ich.  Copper sulfate is also a preferred treatment for protozoan parasites, especially in salt water.  But repeated monitoring of copper is necessary to make sure adequate amounts are available around the clock to effect a cure.

 

Skin and gill flukes can be removed by a formalin "dip", at ten times the indefinite treatment dosage of 1ml per ten gallons.  So at 1ml per 1 gallon for about 20 minutes as a dip, you must remove the fish after 20 minutes or when stress occurs.  Likewise, potassium permanganate dip will also knock flukes off but wont necessarily kill them. Dylox can also be used for flukes at .25 ppm.  Repeat treatments are necessary about every week for three or four treatments to catch unhatched eggs. The best treatment for flukes is praziquantel (Droncit) at 3.5 ppm. 

 

Tapeworms - praziquantel at above treatment dosage.

 

Parasitic copepods like gill lice, fish lice, and anchor worms can be treated with dylox.  Dimulin can also be used but I have never used it and don't have the dosage handy. 

 

Internal protozoan parasites like Hexamita are treated with Metronidazole

 

Roundworms can be treated with the Levamisole.

   

   

Copyright 2002 - The Greater Cincinnati Aquarium Society

GCAS - PO Box 40477 - Cincinnati, Ohio 45240